Hospital bosses in Peterborough and Cambridgeshire are again urging people only to go to A and E if it`s an absolute emergency.
Figures show, in the last two years, 1 in 4 patients could have self-cared or used alternative services.
Officials say that would have saved the local NHS over £4 million, the equivalent of around 700 hip replacements, nearly 300 liver transplants or more than 100 extra dementia nurses.
Meanwhile, Kettering and Northampton General Hospitals are continuing to experience extremely high numbers of people at their A and E departments.
Patients with minor injuries and ailments are being warned they face longer waits than normal as more serious cases are prioritised.
Health bosses are urging those with less serious problems to use alternative NHS services.