New figures show each acute NHS Trust in the East of England including Peterborough and Cambridgshire is currently in the red.
The report by the union Unison also claims 9 out of the 19 Clinical Commissioning Groups in the region are expecting to at best break even or end the year with deficits.
The study’s based on figures from the latest trust board reports.
The union says the pressure on commissioners mean that some have begun to seek savings at the expense of local trusts by cutting budgets, or excluding certain treatments from the NHS, obliging local patients to go private or go without.
Unison is demanding ministers heed these warning signs of crisis taking shape, drop their plans to reduce NHS spending as share of national wealth, and instead bring forward urgently half of the extra £8 billion they promised for the NHS by 2020.