Crews from Stanground, Dogsthorpe and Stamford (Lincs) were called to a road traffic collision on the A1 southbound between Fletton Parkway to Norman Cross.
Seven vehicles were involved in a collision and firefighters used specialist cutting equipment to release one casualty. Ambulance and police were also in attendance.
Watch Commander Matt House said: “this incident involved a large number of vehicles including one which had overturned, and saw the ambulance treat a number of casualties on the scene as well as one person taken to hospital.
“The multi-agency approach h between the fire service, ambulance and air ambulance paramedics and police resulted in the incident being dealt with as quickly and efficiently as possible ensuring the best possible treatment for the casualties involved.
“We’re experiencing lots of changing weather at the moment and we would advise all drivers to take extra care on the roads during these coming days and weeks; drive to the conditions and leave plenty of room between your car and the vehicle in front.”
Crews returned to their stations by 7.40pm.